Background: Community-acquired pneumonia (CAP) remains a significant cause of morbidity and mortality worldwide.
Objectives: To determine and compare the utility/diagnostic accuracy of pneumonia severity scores (CURB-65, NEWS, NEWS-L, and pneumonia severity index) to predict mortality in patients diagnosed with pneumonia in the emergency department.
Methods: This was a hospital based analytical cross-sectional study conducted the Department of Emergency Medicine of a tertiary teaching healthcare facility in India between January 2023 and June 2024.
Results: This study included 210 patients with CAP, with a mortality rate of 10.5%. Non-survivors were older, predominantly female, and had more comorbidities. They exhibited significantly lower systolic and diastolic blood pressure, oxygen saturation, and bicarbonate levels, but higher pulse and respiratory rates, blood urea nitrogen, creatinine, glucose, liver enzymes, sodium, and lactate levels compared to survivors. While haemoglobin, haematocrit, and white blood cell counts were similar between groups, non-survivors had elevated blood glucose, sodium, and lactate levels, and lower blood pH. Mortality prediction scores revealed that non-survivors had significantly higher CURB-65, PSI, NEWS, and NEWS-L scores. Specifically, the NEWS-L score had the highest predictive accuracy, with an area under the curve (AUC) of 0.898, a sensitivity of 85.8%, and a specificity of 96.2%. The NEWS score followed closely with an AUC of 0.890. Both scores outperformed CURB-65 and PSI, highlighting their superior diagnostic accuracy in predicting mortality.
Conclusion: The study demonstrates that elevated vital signs, biochemical markers, and severity scores are associated with higher mortality in pneumonia patients, with NEWS and NEWS-L providing the most accurate predictions.