Ficus krishnae (Moraceae)
is one of the folklore medically important native plant to India. It has been used extensively by ayurvedic practitioner in India to treat various ailments such as ulcers, vomiting, fever, inflammations, leprosy, syphilis, biliousness, dysentery and inflammation of liver. The present study aims the screening of Ficus krishnae
stem bark extracts for in-vitro anti-diabetic study. The in vitro alpha-amylase inhibitory study was performed using different concentration of extract and compared with a standard drug. The results reveal that, there was a dose dependent increase in the percentage inhibitory activity against intestinal enzymes by petroleum ether, chloroform and aqueous extracts. Our findings suggests that the petroleum ether extract and acarbose have an efficient anti-diabetic activity.